4RWP

Crystal structure of porcine OAS1 in complex with dsRNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	2'-5'-oligoadenylate synthase 1	polymer	357	41278.3	1	UniProt (Q29599) Pfam (PF01909) Pfam (PF10421)	Sus scrofa (pigs swine wild boar)	(2-5')oligo(A) synthase 1, 2-5A synthase 1, p42 OAS
2	B (B)	RNA (5'-R(*GP*GP*CP*UP*UP*UP*UP*GP*AP*CP*CP*UP*UP*UP*AP*UP*GP*AP*A)-3')	polymer	19	6017.6	1		synthetic construct
3	C (C)	RNA (5'-R(*UP*UP*CP*AP*UP*AP*AP*AP*GP*GP*UP*CP*AP*AP*AP*AP*GP*CP*C)-3')	polymer	19	6069.7	1		synthetic construct
4	D, E, F (A, B, C)	water	water		18.0	98	Chemie (HOH)

Sequence modifications

A: 1 - 349 (UniProt: Q29599)

PDB	External Database	Details
Gly 350	-	expression tag
Ser 351	-	expression tag
His 352	-	expression tag
His 353	-	expression tag
His 354	-	expression tag
His 355	-	expression tag
His 356	-	expression tag
His 357	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	53365.6
All*	Total formula weight	53365.6

*Water molecules are not included.