4RWN

Crystal structure of the pre-reactive state of porcine OAS1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	2'-5'-oligoadenylate synthase 1	polymer	357	41278.3	1	UniProt (Q29599) Pfam (PF01909) Pfam (PF10421)	Sus scrofa (pigs swine wild boar)	(2-5')oligo(A) synthase 1, 2-5A synthase 1, p42 OAS
2	B (B)	RNA (5'-R(*GP*GP*CP*UP*UP*UP*UP*GP*AP*CP*CP*UP*UP*UP*AP*UP*GP*AP*A)-3')	polymer	19	6017.6	1		synthetic construct
3	C (C)	RNA (5'-R(*UP*UP*CP*AP*UP*AP*AP*AP*GP*GP*UP*CP*AP*AP*AP*AP*GP*CP*C)-3')	polymer	19	6069.7	1		synthetic construct
4	D, E (A)	DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER	non-polymer		505.2	2	Chemie (APC)
5	F, G, H, I (A, B)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
6	J, K, L (A, B, C)	water	water		18.0	253	Chemie (HOH)

Sequence modifications

A: 1 - 349 (UniProt: Q29599)

PDB	External Database	Details
Gly 350	-	expression tag
Ser 351	-	expression tag
His 352	-	expression tag
His 353	-	expression tag
His 354	-	expression tag
His 355	-	expression tag
His 356	-	expression tag
His 357	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	53365.6
Non-Polymers*	Number of molecules	6
	Total formula weight	1107.6
All*	Total formula weight	54473.2

*Water molecules are not included.