4RWD

XFEL structure of the human delta opioid receptor in complex with a bifunctional peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Soluble cytochrome b562,Delta-type opioid receptor	polymer	411	45636.8	2	UniProt (P0ABE7) Pfam (PF07361) Pfam (PF00001) UniProt (by SIFTS) (P41143) In PDB	Escherichia coli	Cytochrome b-562
2	G, H	bifunctional peptide	polymer	5	660.8	2	BIRD (PRD_001256)	synthetic construct
3	A, B	OLEIC ACID	non-polymer		282.5	7	Chemie (OLA)
4	A, B	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
5	A, B	(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate	non-polymer		356.5	3	Chemie (OLC)
6		water	water		18.0	27	Chemie (HOH)

Sequence modifications

A, B: 1001 - 1106 (UniProt: P0ABE7)

PDB	External Database	Details
Gly 996	-	expression tag
Gly 997	-	expression tag
Thr 998	-	expression tag
Thr 999	-	expression tag
Met 1000	-	expression tag
Trp 1007	Met 29	engineered mutation
Ile 1102	His 124	engineered mutation
Leu 1106	Arg 128	engineered mutation

A, B: 39 - 338 (PDB: 4RWD)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	92595.2
Non-Polymers*	Number of molecules	12
	Total formula weight	3092.8
All*	Total formula weight	95688.0

*Water molecules are not included.