4RW3
Structural insights into substrate binding of brown spider venom class II phospholipases D
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Phospholipase D LiSicTox-alphaIA1bii | polymer | 302 | 33739.7 | 1 | UniProt (P0CE82) Pfam (PF13653) In PDB | Loxosceles intermedia (Brown spider) | PLD, Dermonecrotic toxin, Loxtox i4, Sphingomyelin phosphodiesterase D 1, SMD 1, SMase D 1, Sphingomyelinase D 1 |
2 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
3 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
4 | A | D-MYO-INOSITOL-1-PHOSPHATE | non-polymer | 258.1 | 1 | Chemie (IPD) | |||
5 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
6 | A | OCTANOIC ACID (CAPRYLIC ACID) | non-polymer | 144.2 | 1 | Chemie (OCA) | |||
7 | A | HEPTANOIC ACID | non-polymer | 130.2 | 1 | Chemie (SHV) | |||
8 | A | DECANOIC ACID | non-polymer | 172.3 | 2 | Chemie (DKA) | |||
9 | A | PALMITIC ACID | non-polymer | 256.4 | 3 | Chemie (PLM) | |||
10 | A | N-TRIDECANOIC ACID | non-polymer | 214.3 | 1 | Chemie (TDA) | |||
11 | water | water | 18.0 | 168 | Chemie (HOH) |
Sequence modifications
A: 2 - 280 (UniProt: P0CE82)
PDB | External Database | Details |
---|---|---|
Met -21 | - | expression tag |
Gly -20 | - | expression tag |
Ser -19 | - | expression tag |
Ser -18 | - | expression tag |
His -17 | - | expression tag |
His -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
Ser -11 | - | expression tag |
Ser -10 | - | expression tag |
Gly -9 | - | expression tag |
Leu -8 | - | expression tag |
Val -7 | - | expression tag |
Pro -6 | - | expression tag |
Arg -5 | - | expression tag |
Gly -4 | - | expression tag |
Ser -3 | - | expression tag |
His -2 | - | expression tag |
Met -1 | - | expression tag |
Leu 0 | - | expression tag |
Glu 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 33739.7 | |
Non-Polymers* | Number of molecules | 13 |
Total formula weight | 2189.3 | |
All* | Total formula weight | 35929.0 |