4RUI
Crystal structure of a cytochrome P450 2A6 in complex with a monoterpene - sabinene.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | D, A, B, C, E... | Cytochrome P450 2A6 | polymer | 476 | 54671.6 | 6 | UniProt (P11509) Pfam (PF00067) In PDB | Homo sapiens (human) | 1,4-cineole 2-exo-monooxygenase, CYPIIA6, Coumarin 7-hydroxylase, Cytochrome P450 IIA3, Cytochrome P450(I) |
2 | D, A, B, C, E... | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 6 | Chemie (HEM) | |||
3 | D, A, B, C, E... | Sabinene | non-polymer | 136.2 | 6 | Chemie (SNE) | |||
4 | water | water | 18.0 | 312 | Chemie (HOH) |
Sequence modifications
D, A, B, C, E, F: 29 - 494 (UniProt: P11509)
PDB | External Database | Details |
---|---|---|
Met 23 | - | expression tag |
Ala 24 | - | expression tag |
Lys 25 | - | expression tag |
Lys 26 | - | expression tag |
Thr 27 | - | expression tag |
Ser 28 | - | expression tag |
Tyr 392 | Phe 392 | variant |
His 495 | - | expression tag |
His 496 | - | expression tag |
His 497 | - | expression tag |
His 498 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 328029.8 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 4516.3 | |
All* | Total formula weight | 332546.1 |