4RU2

Crystal structure of a RNA-binding protein 39 (RBM39) in complex with fragment of splicing factor (U2AF) from Mus musculus at 2.20 A resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G, I...	RNA-binding protein 39 (RBM39)	polymer	114	12622.3	9	UniProt (Q8VH51) In PDB	Mus musculus (mouse)	Coactivator of activating protein 1 and estrogen receptors, Coactivator of AP-1 and ERs, RNA-binding motif protein 39, RNA-binding region-containing protein 2, Transcription coactivator CAPER
2	B, D, F, H, J...	Splicing factor U2AF 65 kDa subunit	polymer	29	3439.1	9	UniProt (P26369) In PDB	Mus musculus (mouse)	U2 auxiliary factor 65 kDa subunit, U2 snRNP auxiliary factor large subunit
3		water	water		18.0	537	Chemie (HOH)

Sequence modifications

A, C, E, G, I, K, M, O, Q: 418 - 530 (UniProt: Q8VH51)

PDB	External Database	Details
Gly 0	-	expression tag
Tyr 468	Asn 468	engineered mutation

B, D, F, H, J, L, N, P, R: 85 - 112 (UniProt: P26369)

PDB	External Database	Details
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	18
	Total formula weight	144552.6
All*	Total formula weight	144552.6

*Water molecules are not included.