4RT3
Ternary complex crystal structure of DNA polymerase Beta with (alpha, beta)-NH-(beta,gamma)-CH2-dTTP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase beta | polymer | 335 | 38241.7 | 1 | UniProt (P06746) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791) | Homo sapiens (human) | |
| 2 | B (T) | DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3') | polymer | 16 | 4853.2 | 1 | synthetic construct | Template Strand | |
| 3 | C (P) | DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3') | polymer | 10 | 3045.0 | 1 | synthetic construct | Primer Strand | |
| 4 | D (D) | DNA (5'-D(P*GP*TP*CP*GP*G)-3') | polymer | 5 | 1536.0 | 1 | synthetic construct | Downstream Primer Strand | |
| 5 | E (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | F, G, H (A) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 7 | I, J, K (A) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 8 | L (A) | 2'-deoxy-5'-O-[(S)-hydroxy{[(R)-hydroxy(phosphonomethyl)phosphoryl]amino}phosphoryl]-3,4-dihydrothymidine | non-polymer | 479.2 | 1 | Chemie (C6T) | |||
| 9 | M, N, O, P (A, T, P, D) | water | water | 18.0 | 328 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 47675.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 678.8 | |
| All* | Total formula weight | 48354.7 |
