4RRV
Crystal structure of PDK1 in complex with ATP and PIFtide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 3-phosphoinositide-dependent protein kinase 1 | polymer | 311 | 35392.6 | 1 | UniProt (O15530) Pfam (PF00069) | Homo sapiens (human) | hPDK1 |
| 2 | B (B) | Serine/threonine-protein kinase N2 | polymer | 15 | 1995.1 | 1 | UniProt (Q16513) | Homo sapiens | PKN gamma, Protein kinase C-like 2, Protein-kinase C-related kinase 2 |
| 3 | C (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 4 | D, E (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 297 | Chemie (HOH) |
Sequence modifications
A: 50 - 359 (UniProt: O15530)
| PDB | External Database | Details |
|---|---|---|
| Gly 49 | - | expression tag |
| Gly 288 | Tyr 288 | engineered mutation |
| Ala 292 | Gln 292 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37387.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 691.4 | |
| All* | Total formula weight | 38079.0 |
