4RQF
human Seryl-tRNA synthetase dimer complexed with one molecule of tRNAsec
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | selenocysteine tRNA | polymer | 90 | 28948.1 | 1 | Homo sapiens | ||
| 2 | B, C (A, B) | Serine--tRNA ligase, cytoplasmic | polymer | 522 | 59934.4 | 2 | UniProt (P49591) Pfam (PF02403) Pfam (PF00587) | Homo sapiens (human) | Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase |
| 3 | D, G (A, B) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 2 | Chemie (ANP) | |||
| 4 | E, F (A, B) | SERINE | non-polymer | 105.1 | 2 | Chemie (SER) |
Sequence modifications
A, B: 1 - 514 (UniProt: P49591)
| PDB | External Database | Details |
|---|---|---|
| Lys 447 | Glu 447 | engineered mutation |
| Leu 515 | - | expression tag |
| Glu 516 | - | expression tag |
| His 517 | - | expression tag |
| His 518 | - | expression tag |
| His 519 | - | expression tag |
| His 520 | - | expression tag |
| His 521 | - | expression tag |
| His 522 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 148817.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1222.6 | |
| All* | Total formula weight | 150039.6 |
