4RPV
co-crystal structure of Pim1 with compound 3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase pim-1 | polymer | 410 | 46308.2 | 1 | UniProt (P11309) Pfam (PF00069) | Homo sapiens (human) | |
| 2 | B (A) | (3S)-1-{6-[5-(2,6-difluorophenyl)-2H-indazol-3-yl]pyrazin-2-yl}piperidin-3-amine | non-polymer | 406.4 | 1 | Chemie (3UR) |
Sequence modifications
A: -90 - 313 (UniProt: P11309)
| PDB | External Database | Details |
|---|---|---|
| His -96 | - | expression tag |
| His -95 | - | expression tag |
| His -94 | - | expression tag |
| His -93 | - | expression tag |
| His -92 | - | expression tag |
| His -91 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 46308.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 406.4 | |
| All* | Total formula weight | 46714.6 |
