4RPL
Crystal structure of Micobacterium tuberculosis UDP-Galactopyranose mutase in complex with tetrafluorinated substrate analog UDP-F4-Galp
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (B, A, C) | UDP-galactopyranose mutase | polymer | 399 | 45928.3 | 3 | UniProt (P9WIQ1) Pfam (PF13450) Pfam (PF03275) | Mycobacterium tuberculosis | UGM, UDP-GALP mutase, Uridine 5-diphosphate galactopyranose mutase |
| 2 | D, F, H (B, A, C) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 3 | Chemie (FAD) | |||
| 3 | E, G, I (B, A, C) | [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,5S,6R)-3,3,4,4-tetrafluoro-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl dihydrogen diphosphate (non-preferred name) | non-polymer | 606.3 | 3 | Chemie (3UC) | |||
| 4 | J, K, L (B, A, C) | water | water | 18.0 | 421 | Chemie (HOH) |
Sequence modifications
B, A, C: 1 - 399 (UniProt: P9WIQ1)
| PDB | External Database | Details |
|---|---|---|
| Arg 306 | Pro 306 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 137785.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 4175.4 | |
| All* | Total formula weight | 141960.5 |
