4ROE
Human TFIIB-related factor 2 (Brf2) and TBP bound to RPPH1 promoter
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Transcription factor IIIB 50 kDa subunit | polymer | 360 | 40203.4 | 1 | UniProt (Q9HAW0) Pfam (PF21886) | Homo sapiens (human) | TFIIIB50, hTFIIIB50, B-related factor 2, BRF-2, hBRFU |
| 2 | B (B) | TATA-box-binding protein | polymer | 183 | 20597.4 | 1 | UniProt (P20226) Pfam (PF00352) | Homo sapiens (human) | TATA sequence-binding protein, TATA-binding factor, TATA-box factor, Transcription initiation factor TFIID TBP subunit |
| 3 | C (N) | Template strand | polymer | 28 | 8525.6 | 1 | synthetic construct | ||
| 4 | D (T) | Non-template strand | polymer | 28 | 8680.6 | 1 | synthetic construct | ||
| 5 | E, F (N, T) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | G, H, I, J (A, B, N, T) | water | water | 18.0 | 312 | Chemie (HOH) |
Sequence modifications
A: 62 - 419 (UniProt: Q9HAW0)
B: 159 - 339 (UniProt: P20226)
| PDB | External Database | Details |
|---|---|---|
| Gly 60 | - | expression tag |
| Pro 61 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 157 | - | expression tag |
| Pro 158 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 78007.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 48.6 | |
| All* | Total formula weight | 78055.6 |
