4ROE

Human TFIIB-related factor 2 (Brf2) and TBP bound to RPPH1 promoter

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006352	biological_process	DNA-templated transcription initiation
A	0017025	molecular_function	TBP-class protein binding
A	0070897	biological_process	transcription preinitiation complex assembly
B	0003677	molecular_function	DNA binding
B	0006352	biological_process	DNA-templated transcription initiation

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG N 101

Chain	Residue
N	DA18
N	HOH205
N	HOH220
N	HOH221

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG T 101

Chain	Residue
T	DA17
T	HOH222
T	HOH227
T	HOH228
T	HOH234

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Functional Information from PROSITE/UniProt

site_id	PS00351
Number of Residues	50
Details	TFIID Transcription factor TFIID repeat signature. YnPkrFaaVImRirePRttaLIFsSGKMvctGAKseeqsrlAarkyarvV

Chain	Residue	Details
B	TYR192-VAL241
B	TYR283-LEU332

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:27193682, ECO:0007744|PDB:5IYD

Chain	Residue	Details
B	ASN167
B	ARG203
B	LYS218
B	ASN257
B	ARG294

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Cysteine sulfenic acid (-SOH) => ECO:0000269|PubMed:26638071

Chain	Residue	Details
A	CYS361

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