4RMH
Human Sirt2 in complex with SirReal2 and Ac-Lys-H3 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | NAD-dependent protein deacetylase sirtuin-2 | polymer | 304 | 34416.7 | 1 | UniProt (Q8IXJ6) Pfam (PF02146) In PDB | Homo sapiens (human) | Regulatory protein SIR2 homolog 2, SIR2-like protein 2 |
| 2 | B | Ac-Lys-H3 peptide | polymer | 7 | 728.8 | 1 | |||
| 3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | A | 2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]-N-[5-(naphthalen-1-ylmethyl)-1,3-thiazol-2-yl]acetamide | non-polymer | 420.6 | 1 | Chemie (3TE) | |||
| 5 | water | water | 18.0 | 243 | Chemie (HOH) |
Sequence modifications
A: 56 - 356 (UniProt: Q8IXJ6)
| PDB | External Database | Details |
|---|---|---|
| Gly 53 | - | expression tag |
| His 54 | - | expression tag |
| Met 55 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35145.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 486.0 | |
| All* | Total formula weight | 35631.5 |
