4RLS

Lactate Dehydrogenase in complex with inhibitor compound 47

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	L-lactate dehydrogenase A chain	polymer	331	36603.5	4	UniProt (P00338) Pfam (PF00056) Pfam (PF02866)	Homo sapiens (human)	LDH-A, Cell proliferation-inducing gene 19 protein, LDH muscle subunit, LDH-M, Renal carcinoma antigen NY-REN-59
2	E, G, I, L (A, B, C, D)	1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE	non-polymer		665.4	4	Chemie (NAI)
3	F, J (A, C)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
4	H, K (B, C)	(2S)-2-HYDROXYPROPANOIC ACID	non-polymer		90.1	2	Chemie (2OP)
5	M (D)	(1R)-5'-[(2-chlorophenyl)sulfanyl]-4'-hydroxy-2,3-dihydrospiro[indene-1,2'-pyran]-6'(3'H)-one	non-polymer		358.8	1	Chemie (49C)
6	N, O, P, Q (A, B, C, D)	water	water		18.0	748	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	146413.9
Non-Polymers*	Number of molecules	9
	Total formula weight	3392.9
All*	Total formula weight	149806.8

*Water molecules are not included.