4RLH

Crystal structure of enoyl ACP reductase from Burkholderia pseudomallei in complex with AFN-1252

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, D, C)	Enoyl-[acyl-carrier-protein] reductase [NADH]	polymer	272	28968.0	4	UniProt (Q63SW7) Pfam (PF13561)	Burkholderia pseudomallei
2	E, F, G, H (A, B, D, C)	N-methyl-N-[(3-methyl-1-benzofuran-2-yl)methyl]-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)propanamide	non-polymer		377.4	4	Chemie (0WE)
3	I, J, K, L (A, B, D, C)	water	water		18.0	541	Chemie (HOH)

Sequence modifications

A, B, D, C: 1 - 263 (UniProt: Q63SW7)

PDB	External Database	Details
His -8	-	expression tag
Met -7	-	expression tag
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	115871.9
Non-Polymers*	Number of molecules	4
	Total formula weight	1509.7
All*	Total formula weight	117381.7

*Water molecules are not included.