4RLH
Crystal structure of enoyl ACP reductase from Burkholderia pseudomallei in complex with AFN-1252
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| C | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
| C | 0006633 | biological_process | fatty acid biosynthetic process |
| D | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
| D | 0006633 | biological_process | fatty acid biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 0WE A 500 |
| Chain | Residue |
| A | PHE94 |
| A | ALA95 |
| A | ARG97 |
| A | TYR146 |
| A | ASN155 |
| A | TYR156 |
| A | MET159 |
| A | PHE203 |
| A | HOH637 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 0WE B 500 |
| Chain | Residue |
| B | PHE94 |
| B | ALA95 |
| B | TYR146 |
| B | ASN155 |
| B | TYR156 |
| B | MET159 |
| B | ILE200 |
| B | PHE203 |
| B | ILE206 |
| B | HOH648 |
| B | HOH720 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 0WE D 500 |
| Chain | Residue |
| D | PHE94 |
| D | ALA95 |
| D | ARG97 |
| D | ILE100 |
| D | TYR146 |
| D | ASN155 |
| D | TYR156 |
| D | PHE203 |
| D | HOH626 |
| D | HOH688 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 0WE C 500 |
| Chain | Residue |
| C | PHE94 |
| C | ALA95 |
| C | ARG97 |
| C | ILE100 |
| C | TYR146 |
| C | ASN155 |
| C | TYR156 |
| C | LYS163 |
| C | ALA196 |
| C | ILE200 |
| C | HOH634 |
