4RKK
Structure of a product bound phosphatase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, C) | Laforin | polymer | 332 | 37267.5 | 2 | UniProt (O95278) Pfam (PF00686) Pfam (PF00782) | Homo sapiens (human) | Glucan phosphatase, Lafora PTPase, LAFPTPase |
| 2 | C, E, F (B, E, F) | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 990.9 | 3 | In PDB BIRD (PRD_900035) GlyTouCan (G91368RN) | alpha-maltohexaose | ||
| 3 | D, G (D, G) | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 504.4 | 2 | In PDB BIRD (PRD_900009) GlyTouCan (G96370VA) | alpha-maltotriose | ||
| 4 | H (H) | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 666.6 | 1 | In PDB BIRD (PRD_900010) GlyTouCan (G87171PZ) | alpha-maltotetraose | ||
| 5 | I, K (A, C) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 6 | J, L (A, C) | alpha-D-glucopyranose | non-polymer | 180.2 | 2 | Chemie (GLC) | |||
| 7 | M, N (A, C) | water | water | 18.0 | 144 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 329 (UniProt: O95278)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Ser 266 | Cys 266 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 74535.0 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 4648.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 550.3 | |
| All* | Total formula weight | 79733.2 |
