4RI0

Serine Protease HtrA3, mutationally inactivated

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Serine protease HTRA3	polymer	332	36312.3	3	UniProt (P83110) Pfam (PF13365) Pfam (PF13180) In PDB	Homo sapiens (human)	High-temperature requirement factor A3, Pregnancy-related serine protease
2	A	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
3		water	water		18.0	3	Chemie (HOH)

Sequence modifications

A, B, C: 130 - 453 (UniProt: P83110)

PDB	External Database	Details
Ala 305	Ser 305	engineered mutation
Gly 454	-	expression tag
Gly 455	-	expression tag
His 456	-	expression tag
His 457	-	expression tag
His 458	-	expression tag
His 459	-	expression tag
His 460	-	expression tag
His 461	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	108936.9
Non-Polymers*	Number of molecules	2
	Total formula weight	189.9
All*	Total formula weight	109126.8

*Water molecules are not included.