4RI0

Serine Protease HtrA3, mutationally inactivated

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004252	molecular_function	serine-type endopeptidase activity
A	0006508	biological_process	proteolysis
B	0004252	molecular_function	serine-type endopeptidase activity
B	0006508	biological_process	proteolysis
C	0004252	molecular_function	serine-type endopeptidase activity
C	0006508	biological_process	proteolysis

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PO4 A 501

Chain	Residue
A	LYS354
A	GLY455
A	HIS457
A	HIS458

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PO4 A 502

Chain	Residue
A	GLN423
A	PHE356
A	ILE357
A	GLY358
A	ILE359
A	MET361

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	ACT_SITE: Charge relay system => ECO:0000269|PubMed:26110759

Chain	Residue	Details
A	HIS191
A	ASP227
B	HIS191
B	ASP227
C	HIS191
C	ASP227

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site_id	SWS_FT_FI2
Number of Residues	3
Details	ACT_SITE: Charge relay system => ECO:0000269|PubMed:22229724, ECO:0000269|PubMed:26110759

Chain	Residue	Details
A	ALA305
B	ALA305
C	ALA305

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