4RHX
Structures of Mycobacterium tuberculosis 6-oxopurine phosphoribosyltransferase which is a potential target for drug development against this disease
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Hypoxanthine-guanine phosphoribosyltransferase | polymer | 201 | 22140.9 | 4 | UniProt (A5U8U8) Pfam (PF00156) UniProt (by SIFTS) (P9WHQ9) In PDB | Mycobacterium tuberculosis | |
| 2 | A, B, C, D | [2-([2-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)ethyl]{2-[(2-oxoethyl)(2-phosphonoethyl)amino]ethyl}amino)ethyl]phosphonic acid | non-polymer | 495.4 | 4 | Chemie (3QF) | |||
| 3 | A, B, C, D | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) | |||
| 4 | water | water | 18.0 | 552 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 88563.7 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2175.9 | |
| All* | Total formula weight | 90739.6 |
