4RHX

Structures of Mycobacterium tuberculosis 6-oxopurine phosphoribosyltransferase which is a potential target for drug development against this disease

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Hypoxanthine-guanine phosphoribosyltransferase	polymer	201	22140.9	4	UniProt (A5U8U8) Pfam (PF00156) UniProt (by SIFTS) (P9WHQ9)	Mycobacterium tuberculosis
2	E, H, K, N (A, B, C, D)	[2-([2-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)ethyl]{2-[(2-oxoethyl)(2-phosphonoethyl)amino]ethyl}amino)ethyl]phosphonic acid	non-polymer		495.4	4	Chemie (3QF)
3	F, G, I, J, L... (A, B, C, D)	MAGNESIUM ION	non-polymer		24.3	8	Chemie (MG)
4	Q, R, S, T (A, B, C, D)	water	water		18.0	552	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	88563.7
Non-Polymers*	Number of molecules	12
	Total formula weight	2175.9
All*	Total formula weight	90739.6

*Water molecules are not included.