4RH5
Crystal structure of PTPN3 (PTPH1) in complex with Eps15 pTyr849 peptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Tyrosine-protein phosphatase non-receptor type 3 | polymer | 306 | 34887.7 | 1 | UniProt (P26045) Pfam (PF00102) In PDB | Homo sapiens (human) | Protein-tyrosine phosphatase H1, PTP-H1 |
2 | B | Epidermal growth factor receptor substrate 15 | polymer | 9 | 1124.0 | 1 | UniProt (P42566) In PDB | Homo sapiens | Protein Eps15, Protein AF-1p |
3 | water | water | 18.0 | 258 | Chemie (HOH) |
Sequence modifications
A: 628 - 909 (UniProt: P26045)
PDB | External Database | Details |
---|---|---|
Met 604 | - | expression tag |
His 605 | - | expression tag |
His 606 | - | expression tag |
His 607 | - | expression tag |
His 608 | - | expression tag |
His 609 | - | expression tag |
His 610 | - | expression tag |
Ser 611 | - | expression tag |
Ser 612 | - | expression tag |
Gly 613 | - | expression tag |
Val 614 | - | expression tag |
Asp 615 | - | expression tag |
Leu 616 | - | expression tag |
Gly 617 | - | expression tag |
Thr 618 | - | expression tag |
Glu 619 | - | expression tag |
Asn 620 | - | expression tag |
Leu 621 | - | expression tag |
Tyr 622 | - | expression tag |
Phe 623 | - | expression tag |
Gln 624 | - | expression tag |
Ser 625 | - | expression tag |
Asn 626 | - | expression tag |
Ala 627 | - | expression tag |
Ala 811 | Asp 811 | engineered mutation |
Ser 842 | Cys 842 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 36011.7 | |
All* | Total formula weight | 36011.7 |