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4RH3

AMPPCP-bound structure of human platelet phosphofructokinase in an R-state, crystal form II

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
ATP-dependent 6-phosphofructokinase, platelet typepolymer74381111.84UniProt (Q01813)
Pfam (PF00365)
Homo sapiens (human)ATP-PFK, PFK-P, 6-phosphofructokinase type C, Phosphofructo-1-kinase isozyme C, PFK-C, Phosphohexokinase
2E, J, K, N
(A, B, C, D)
PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTERnon-polymer505.24Chemie (ACP)
3F, G, H, I, L...
(A, B, C, D)
PHOSPHATE IONnon-polymer95.07Chemie (PO4)
Sequence modifications
A, B, C, D: 26 - 762 (UniProt: Q01813)
PDBExternal DatabaseDetails
Val 20-expression tag
Pro 21-expression tag
Asp 22-expression tag
Pro 23-expression tag
Thr 24-expression tag
Ser 25-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight324447.4
Non-Polymers*Number of molecules11
Total formula weight2685.6
All*Total formula weight327133.0
*Water molecules are not included.

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PDB entries from 2025-12-24

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