4RFN
Crystal structure of ADCC-potent Rhesus macaque ANTIBODY JR4 in complex with HIV-1 CLADE A/E GP120 and M48
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (G, A) | HIV-1 CLADE A/E 93TH057 (H375S) GP120 | polymer | 353 | 39160.4 | 2 | Pfam (PF00516) UniProt (by SIFTS) (Q0ED31) | Human immunodeficiency virus 1 (HIV-1) | |
| 2 | B, F (H, B) | FAB HEAVY CHAIN OF ADCC ANTI-HIV-1 ANTIBODY JR4 | polymer | 233 | 24847.8 | 2 | Macaca mulatta (rhesus macaque) | ||
| 3 | C, G (L, C) | FAB LIGHT CHAIN OF ADCC ANTI-HIV-1 ANTIBODY JR4 | polymer | 216 | 22719.1 | 2 | Macaca mulatta (rhesus macaque) | ||
| 4 | D, H (M, D) | T-CELL SURFACE GLYCOPROTEIN CD4 mimetic M48 | polymer | 28 | 2944.6 | 2 | synthetic construct | ||
| 5 | I, J, K, L, M... (G, A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 18 | Chemie (NAG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 179343.8 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 3981.7 | |
| All* | Total formula weight | 183325.6 |
