4REQ
Methylmalonyl-COA Mutase substrate complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | METHYLMALONYL-COA MUTASE | polymer | 727 | 80137.9 | 2 | UniProt (P11653) | Propionibacterium freudenreichii subsp. shermanii | |
| 2 | B, D (B, D) | METHYLMALONYL-COA MUTASE | polymer | 637 | 69430.2 | 2 | UniProt (P11652) | Propionibacterium freudenreichii subsp. shermanii | |
| 3 | E, K (A, C) | COBALAMIN | non-polymer | 1330.4 | 2 | Chemie (B12) | |||
| 4 | F, L (A, C) | SUCCINYL-COENZYME A | non-polymer | 867.6 | 2 | Chemie (SCA) PubChem (1111) PubChem (23640744) PubChem (46936759) PubChem (92133) PubChem (439161) PubChem (87657600) PubChem (162863677) | |||
| 5 | G, N (A, C) | METHYLMALONYL-COENZYME A | non-polymer | 867.6 | 2 | Chemie (MCA) PubChem (21252287) PubChem (22833590) PubChem (23640742) PubChem (123909) PubChem (177678920) PubChem (44229127) PubChem (46936873) PubChem (613) PubChem (87646595) PubChem (439291) PubChem (439439) PubChem (439754) PubChem (449534) PubChem (11966111) PubChem (135084526) PubChem (164834694) PubChem (172638396) | |||
| 6 | H, M (A, C) | 5'-DEOXYADENOSINE | non-polymer | 251.2 | 2 | Chemie (5AD) PubChem (16725083) PubChem (142) PubChem (71678) PubChem (23638944) PubChem (439182) PubChem (25201172) PubChem (25796474) PubChem (25796475) PubChem (40467848) PubChem (23615209) PubChem (449044) PubChem (40467849) PubChem (1277776) PubChem (57115448) PubChem (59731278) PubChem (6398669) PubChem (6928544) PubChem (90321697) PubChem (676784) PubChem (12827542) PubChem (6541038) PubChem (121275112) PubChem (124363198) PubChem (133636852) PubChem (140689696) PubChem (142801875) PubChem (142801934) | |||
| 7 | I, J, O, P (A, B, C, D) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) PubChem (753) | |||
| 8 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 1286 | Chemie (HOH) |
Sequence modifications
B, D: 2 - 638 (UniProt: P11652)
| PDB | External Database | Details |
|---|---|---|
| Gly 203 | Ala 202 | SEE REMARK 999 |
| Glu 330 | Asp 329 | SEE REMARK 999 |
| Leu 331 | Val 330 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 299136.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 7002.0 | |
| All* | Total formula weight | 306138.1 |
