4REC
A nuclease-DNA complex form 3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Fanconi-associated nuclease 1 | polymer | 647 | 73653.9 | 1 | UniProt (Q9Y2M0) Pfam (PF21315) Pfam (PF21169) Pfam (PF21170) Pfam (PF08774) | Homo sapiens (human) | FANCD2/FANCI-associated nuclease 1, Myotubularin-related protein 15 |
| 2 | B (B) | DNA (40-MER) | polymer | 40 | 12316.9 | 1 | SYNTHETIC CONSTRUCT | ||
| 3 | C, D, E (A) | IODIDE ION | non-polymer | 126.9 | 3 | Chemie (IOD) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 245 | Chemie (HOH) |
Sequence modifications
A: 373 - 1017 (UniProt: Q9Y2M0)
| PDB | External Database | Details |
|---|---|---|
| Glu 371 | - | expression tag |
| Phe 372 | - | expression tag |
| Ala 960 | Asp 960 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 85970.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 380.7 | |
| All* | Total formula weight | 86351.5 |
