4RAK

Crystal structure of nuclear receptor subfamily 1, group h, member 2 (lxrb) complexed with partial agonist

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Oxysterols receptor LXR-beta	polymer	264	30542.9	2	UniProt (P55055) Pfam (PF00104)	Homo sapiens (human)	Liver X receptor beta, Nuclear receptor NER, Nuclear receptor subfamily 1 group H member 2, Ubiquitously-expressed nuclear receptor
2	C, D, F (A, B)	1,4-BUTANEDIOL	non-polymer		90.1	3	Chemie (BU1)
3	E, G (A, B)	2-{2-[2-(2-chlorophenyl)propan-2-yl]-1-[3'-(methylsulfonyl)biphenyl-4-yl]-1H-imidazol-4-yl}propan-2-ol	non-polymer		509.1	2	Chemie (652)
4	H, I (A, B)	water	water		18.0	183	Chemie (HOH)

Sequence modifications

A, B: 214 - 461 (UniProt: P55055)

PDB	External Database	Details
Met 198	-	expression tag
His 199	-	expression tag
His 200	-	expression tag
His 201	-	expression tag
His 202	-	expression tag
His 203	-	expression tag
His 204	-	expression tag
Gly 205	-	expression tag
Glu 206	-	expression tag
Asn 207	-	expression tag
Leu 208	-	expression tag
Tyr 209	-	expression tag
Phe 210	-	expression tag
Gln 211	-	expression tag
Gly 212	-	expression tag
Ser 213	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	61085.7
Non-Polymers*	Number of molecules	5
	Total formula weight	1288.5
All*	Total formula weight	62374.2

*Water molecules are not included.