4R9U
Structure of vitamin B12 transporter BtuCD in a nucleotide-bound outward facing state
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Vitamin B12 import system permease protein BtuC | polymer | 333 | 35484.3 | 2 | UniProt (P06609) Pfam (PF01032) In PDB | Escherichia coli | |
2 | C, D | Vitamin B12 import ATP-binding protein BtuD | polymer | 249 | 27086.2 | 2 | UniProt (P06611) Pfam (PF00005) In PDB | Escherichia coli | Vitamin B12-transporting ATPase |
3 | A, B | LAURYL DIMETHYLAMINE-N-OXIDE | non-polymer | 229.4 | 4 | Chemie (LDA) | |||
4 | C, D | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 2 | Chemie (ANP) | |||
5 | C, D | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) |
Sequence modifications
A, B: 1 - 326 (UniProt: P06609)
C, D: 1 - 249 (UniProt: P06611)
PDB | External Database | Details |
---|---|---|
Gly -6 | - | expression tag |
Pro -5 | - | expression tag |
Ser -4 | - | expression tag |
Gly -3 | - | expression tag |
Thr -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Ser 18 | Cys 18 | engineered mutation |
Ser 32 | Cys 32 | engineered mutation |
Ser 120 | Cys 120 | engineered mutation |
Ser 156 | Cys 156 | engineered mutation |
Ser 205 | Cys 205 | engineered mutation |
Ser 206 | Cys 206 | engineered mutation |
Ser 267 | Cys 267 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gln 159 | Glu 159 | engineered mutation |
Cys 162 | Asn 162 | engineered mutation |
Ser 180 | Cys 180 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 125140.9 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1978.6 | |
All* | Total formula weight | 127119.5 |