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4R8M

Human SIRT2 crystal structure in complex with BHJH-TM1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
NAD-dependent protein deacetylase sirtuin-2polymer31936159.72UniProt (Q8IXJ6)
Pfam (PF02146)
Homo sapiens (human)Regulatory protein SIR2 homolog 2, SIR2-like protein 2
2C, D
(C, D)
BHJH-TM1 peptidepolymer5531.62
3E, F
(A, B)
ZINC IONnon-polymer65.42Chemie (ZN)
4G, H
(C, D)
tridecanethialnon-polymer214.42Chemie (3LX)
5I, J
(A, B)
waterwater18.027Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight73382.7
Non-Polymers*Number of molecules4
Total formula weight559.6
All*Total formula weight73942.4
*Water molecules are not included.

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PDB entries from 2026-01-14

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