4R8D

Crystal structure of Rv1600 encoded aminotransferase in complex with PLP-MES from Mycobacterium tuberculosis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Histidinol-phosphate aminotransferase	polymer	394	42278.8	2	UniProt (I6XYD8) Pfam (PF00155) UniProt (by SIFTS) (P9WML7)	Mycobacterium tuberculosis H37Rv	Imidazole acetol-phosphate transaminase
2	C, H (A, B)	PYRIDOXAL-5'-PHOSPHATE	non-polymer		247.1	2	Chemie (PLP)
3	D, I (A, B)	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	2	Chemie (MES)
4	E, F, G, J (A, B)	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
5	K, L (A, B)	water	water		18.0	271	Chemie (HOH)

Sequence modifications

A, B: 1 - 380 (UniProt: I6XYD8)

PDB	External Database	Details
Met 0	-	expression tag
Lys 381	-	expression tag
Leu 382	-	expression tag
Ala 383	-	expression tag
Ala 384	-	expression tag
Ala 385	-	expression tag
Leu 386	-	expression tag
Glu 387	-	expression tag
His 388	-	expression tag
His 389	-	expression tag
His 390	-	expression tag
His 391	-	expression tag
His 392	-	expression tag
His 393	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	84557.6
Non-Polymers*	Number of molecules	8
	Total formula weight	1269.0
All*	Total formula weight	85826.7

*Water molecules are not included.