4R7C
Crystal Structure of CNG mimicking NaK-ETPP mutant cocrystallized with DiMethylammonium
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Potassium channel protein | polymer | 96 | 10626.6 | 4 | UniProt (Q81HW2) Pfam (PF07885) | Bacillus cereus ATCC 14579 | |
| 2 | AB, E, F, G, H... (C, A, D, B) | GLYCINE | non-polymer | 75.1 | 29 | Chemie (GLY) | |||
| 3 | AA, BA, BB, CA, CB... (B, C, A) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 9 | Chemie (MPD) | |||
| 4 | DB, EA, EB, FA, FB... (C, B, D, A) | DIMETHYLAMINE | non-polymer | 45.1 | 25 | Chemie (DMN) | |||
| 5 | PB, QB, RB, SB (A, B, C, D) | water | water | 18.0 | 69 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 20 - 109 (UniProt: Q81HW2)
| PDB | External Database | Details |
|---|---|---|
| Met 18 | - | expression tag |
| Ala 19 | - | expression tag |
| Glu 66 | Asp 66 | engineered mutation |
| Thr 67 | Gly 67 | engineered mutation |
| Pro 68 | Asn 68 | engineered mutation |
| Pro 69 | Phe 69 | engineered mutation |
| - | Ser 70 | deletion |
| Leu 110 | - | expression tag |
| Val 111 | - | expression tag |
| Pro 112 | - | expression tag |
| Arg 113 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 42506.2 | |
| Non-Polymers* | Number of molecules | 63 |
| Total formula weight | 4367.6 | |
| All* | Total formula weight | 46873.8 |
