4R7C
Crystal Structure of CNG mimicking NaK-ETPP mutant cocrystallized with DiMethylammonium
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005267 | molecular_function | potassium channel activity |
| A | 0016020 | cellular_component | membrane |
| A | 0071805 | biological_process | potassium ion transmembrane transport |
| B | 0005267 | molecular_function | potassium channel activity |
| B | 0016020 | cellular_component | membrane |
| B | 0071805 | biological_process | potassium ion transmembrane transport |
| C | 0005267 | molecular_function | potassium channel activity |
| C | 0016020 | cellular_component | membrane |
| C | 0071805 | biological_process | potassium ion transmembrane transport |
| D | 0005267 | molecular_function | potassium channel activity |
| D | 0016020 | cellular_component | membrane |
| D | 0071805 | biological_process | potassium ion transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GLY A 201 |
| Chain | Residue |
| A | PHE28 |
| A | ILE32 |
| B | PHE84 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GLY A 202 |
| Chain | Residue |
| A | HIS95 |
| A | GLY204 |
| A | HOH304 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GLY A 203 |
| Chain | Residue |
| A | MPD210 |
| A | PHE78 |
| A | LEU81 |
| A | TYR82 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GLY A 204 |
| Chain | Residue |
| A | LYS20 |
| A | ASP21 |
| A | GLY202 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GLY A 205 |
| Chain | Residue |
| A | ASN109 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MPD A 208 |
| Chain | Residue |
| A | PRO50 |
| A | ILE51 |
| C | LEU110 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MPD A 209 |
| Chain | Residue |
| A | LYS20 |
| A | PHE28 |
| A | HOH305 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MPD A 210 |
| Chain | Residue |
| A | PHE74 |
| A | LEU81 |
| A | GLY203 |
| A | HOH310 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE DMN A 211 |
| Chain | Residue |
| A | SER37 |
| site_id | BC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE DMN A 212 |
| Chain | Residue |
| A | ALA98 |
| site_id | BC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE DMN B 201 |
| Chain | Residue |
| A | THR63 |
| A | THR63 |
| A | VAL64 |
| A | VAL64 |
| A | GLY65 |
| A | GLY65 |
| B | THR63 |
| B | THR63 |
| B | VAL64 |
| B | VAL64 |
| B | GLY65 |
| B | GLY65 |
| B | HOH303 |
| B | HOH303 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GLY B 202 |
| Chain | Residue |
| B | ASP73 |
| B | PHE74 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GLY B 204 |
| Chain | Residue |
| B | ILE32 |
| B | GLY206 |
| site_id | BC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GLY B 205 |
| Chain | Residue |
| B | ASN109 |
| D | ILE77 |
| site_id | BC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GLY B 206 |
| Chain | Residue |
| B | GLY204 |
| B | GLY209 |
| site_id | BC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GLY B 207 |
| Chain | Residue |
| B | THR72 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GLY B 209 |
| Chain | Residue |
| B | ILE32 |
| B | GLY206 |
| C | SER37 |
| site_id | BC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GLY B 210 |
| Chain | Residue |
| A | PHE91 |
| B | HIS95 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MPD B 211 |
| Chain | Residue |
| B | LEU33 |
| B | ILE36 |
| B | SER37 |
| B | MPD213 |
| C | PHE78 |
| C | GLY207 |
| site_id | CC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MPD B 212 |
| Chain | Residue |
| B | LEU81 |
| B | ILE85 |
| B | DMN216 |
| B | HOH309 |
| site_id | CC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MPD B 213 |
| Chain | Residue |
| B | SER37 |
| B | ILE40 |
| B | MPD211 |
| C | ILE85 |
| site_id | CC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MPD B 214 |
| Chain | Residue |
| A | ILE106 |
| B | GLU23 |
| B | VAL26 |
| site_id | CC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE DMN B 215 |
| Chain | Residue |
| B | ASP21 |
| B | GLU23 |
| site_id | CC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE DMN B 216 |
| Chain | Residue |
| B | SER37 |
| B | MPD212 |
| site_id | CC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE DMN B 217 |
| Chain | Residue |
| A | GLN102 |
| site_id | CC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE DMN B 218 |
| Chain | Residue |
| B | ASP52 |
| B | THR67 |
| B | PRO68 |
| site_id | CC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE DMN B 219 |
| Chain | Residue |
| B | ARG49 |
| site_id | DC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE DMN B 220 |
| Chain | Residue |
| B | DMN221 |
| site_id | DC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE DMN B 221 |
| Chain | Residue |
| B | DMN220 |
| B | DMN223 |
| site_id | DC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE DMN B 223 |
| Chain | Residue |
| B | DMN221 |
| site_id | DC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE DMN B 224 |
| Chain | Residue |
| B | PRO69 |
| B | GLN71 |
| B | HOH313 |
| site_id | DC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE DMN B 225 |
| Chain | Residue |
| B | ILE77 |
| site_id | DC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE DMN B 227 |
| Chain | Residue |
| B | HOH311 |
| B | HOH318 |
| site_id | DC7 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE DMN C 201 |
| Chain | Residue |
| D | THR63 |
| D | VAL64 |
| D | VAL64 |
| C | THR63 |
| C | THR63 |
| C | VAL64 |
| C | VAL64 |
| C | GLY65 |
| C | GLY65 |
| C | HOH304 |
| C | HOH304 |
| D | THR63 |
| site_id | DC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GLY C 202 |
| Chain | Residue |
| C | GLN25 |
| C | MPD211 |
| site_id | DC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GLY C 203 |
| Chain | Residue |
| C | HOH322 |
| site_id | EC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GLY C 204 |
| Chain | Residue |
| C | ARG49 |
| C | PRO50 |
| C | ILE51 |
| site_id | EC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GLY C 205 |
| Chain | Residue |
| C | PHE56 |
| C | PRO68 |
| C | PRO69 |
| C | MPD212 |
| C | HOH310 |
| site_id | EC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GLY C 206 |
| Chain | Residue |
| C | LEU61 |
| C | THR62 |
| C | ILE87 |
| C | PHE91 |
| site_id | EC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GLY C 207 |
| Chain | Residue |
| B | MPD211 |
| C | THR34 |
| C | SER37 |
| site_id | EC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GLY C 208 |
| Chain | Residue |
| C | LEU97 |
| C | ALA98 |
| C | GLN102 |
| C | HOH320 |
| D | ILE85 |
| site_id | EC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GLY C 209 |
| Chain | Residue |
| B | ARG113 |
| site_id | EC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GLY C 210 |
| Chain | Residue |
| C | LEU54 |
| C | DMN213 |
| site_id | EC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MPD C 211 |
| Chain | Residue |
| C | PHE24 |
| C | ASN100 |
| C | GLY202 |
| site_id | EC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MPD C 212 |
| Chain | Residue |
| C | ASP52 |
| C | PRO68 |
| C | GLY205 |
| site_id | FC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE DMN C 213 |
| Chain | Residue |
| C | GLY210 |
| site_id | FC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE DMN C 214 |
| Chain | Residue |
| C | PHE28 |
| C | PHE93 |
| C | LEU97 |
| site_id | FC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DMN C 215 |
| Chain | Residue |
| C | THR67 |
| C | PRO68 |
| C | DMN216 |
| C | HOH314 |
| C | HOH323 |
| D | GLU66 |
| D | THR67 |
| site_id | FC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DMN C 216 |
| Chain | Residue |
| C | PRO68 |
| C | DMN215 |
| C | HOH324 |
| D | PRO68 |
| site_id | FC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GLY D 201 |
| Chain | Residue |
| A | LEU33 |
| A | ILE36 |
| A | HOH303 |
| D | PHE78 |
| D | ILE85 |
| site_id | FC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GLY D 202 |
| Chain | Residue |
| A | ILE32 |
| D | ILE40 |
| site_id | FC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GLY D 204 |
| Chain | Residue |
| D | ILE36 |
| site_id | FC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE DMN D 205 |
| Chain | Residue |
| D | ASP52 |
| D | THR67 |
| site_id | FC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE DMN D 206 |
| Chain | Residue |
| D | LEU35 |
