4R76
Structure of the m17 leucyl aminopeptidase from malaria complexed with a hydroxamic acid-based inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | M17 family aminopeptidase | polymer | 528 | 58709.0 | 12 | Pfam (PF00883) UniProt (by SIFTS) (Q8IL11) | Plasmodium falciparum fcb1/columbia | |
| 2 | AA, BC, CA, CB, EA... (C, L, D, H, E...) | ZINC ION | non-polymer | 65.4 | 24 | Chemie (ZN) | |||
| 3 | AC, DA, DB, HA, JB... (L, D, H, E, I...) | CARBONATE ION | non-polymer | 60.0 | 12 | Chemie (CO3) | |||
| 4 | BA, CC, FA, FB, JA... (C, L, D, H, E...) | 3-amino-N-{(1R)-2-(hydroxyamino)-2-oxo-1-[4-(1H-pyrazol-1-yl)phenyl]ethyl}benzamide | non-polymer | 351.4 | 12 | Chemie (R5X) | |||
| 5 | GB, KA, NA, Q, R... (H, E, A, F, K) | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 6 | AB, BB, DC, HB, LA... (G, L, H, E, I...) | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 15 | Chemie (1PE) | |||
| 7 | EC, FC, GC, HC, IC... (A, B, C, D, E...) | water | water | 18.0 | 1796 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 704507.7 | |
| Non-Polymers* | Number of molecules | 70 |
| Total formula weight | 10752.8 | |
| All* | Total formula weight | 715260.5 |
