4R76

Structure of the m17 leucyl aminopeptidase from malaria complexed with a hydroxamic acid-based inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	M17 family aminopeptidase	polymer	528	58709.0	12	Pfam (PF00883) UniProt (by SIFTS) (Q8IL11) In PDB	Plasmodium falciparum fcb1/columbia
2	C, L, D, H, E...	ZINC ION	non-polymer		65.4	24	Chemie (ZN)
3	L, D, H, E, I...	CARBONATE ION	non-polymer		60.0	12	Chemie (CO3)
4	C, L, D, H, E...	3-amino-N-{(1R)-2-(hydroxyamino)-2-oxo-1-[4-(1H-pyrazol-1-yl)phenyl]ethyl}benzamide	non-polymer		351.4	12	Chemie (R5X)
5	H, E, A, F, K	SULFATE ION	non-polymer		96.1	7	Chemie (SO4)
6	G, L, H, E, I...	PENTAETHYLENE GLYCOL	non-polymer		238.3	15	Chemie (1PE)
7		water	water		18.0	1796	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	704507.7
Non-Polymers*	Number of molecules	70
	Total formula weight	10752.8
All*	Total formula weight	715260.5

*Water molecules are not included.