4R3Z

Crystal structure of human ArgRS-GlnRS-AIMP1 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Aminoacyl tRNA synthase complex-interacting multifunctional protein 1	polymer	312	34404.7	1	UniProt (Q12904) Pfam (PF01588) In PDB	Homo sapiens (human)	Multisynthase complex auxiliary component p43, Endothelial monocyte-activating polypeptide 2, EMAP-2, Endothelial monocyte-activating polypeptide II, EMAP-II, Small inducible cytokine subfamily E member 1
2	B	Arginine--tRNA ligase, cytoplasmic	polymer	675	77230.8	1	UniProt (P54136) Pfam (PF03485) Pfam (PF00750) Pfam (PF05746) In PDB	Homo sapiens (human)	Arginyl-tRNA synthetase, ArgRS
3	C	Glutamine--tRNA ligase	polymer	799	90519.6	1	UniProt (P47897) Pfam (PF04558) Pfam (PF04557) Pfam (PF00749) Pfam (PF03950) Pfam (PF20974) In PDB	Homo sapiens (human)	Glutaminyl-tRNA synthetase, GlnRS

Sequence modifications

B: 1 - 660 (UniProt: P54136)

PDB	External Database	Details
Met -14	-	expression tag
Gly -13	-	expression tag
Ser -12	-	expression tag
Ser -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
Ser -4	-	expression tag
Gln -3	-	expression tag
Asp -2	-	expression tag
Pro -1	-	expression tag
Met 0	-	expression tag

C: 1 - 775 (UniProt: P47897)

PDB	External Database	Details
His -23	-	expression tag
Gly -22	-	expression tag
Ser -21	-	expression tag
Ser -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
Ser -13	-	expression tag
Ser -12	-	expression tag
Gly -11	-	expression tag
Leu -10	-	expression tag
Val -9	-	expression tag
Pro -8	-	expression tag
Arg -7	-	expression tag
Gly -6	-	expression tag
Ser -5	-	expression tag
His -4	-	expression tag
Met -3	-	expression tag
Ala -2	-	expression tag
Ser -1	-	expression tag
Met 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	202155.0
All*	Total formula weight	202155.0

*Water molecules are not included.