4R1F
Re-refined Human DNA topoisomerase IIa (ATPase and transducer domains) in complex with ADP and SO4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | DNA topoisomerase 2-alpha | polymer | 400 | 45660.5 | 4 | UniProt (P11388) Pfam (PF02518) Pfam (PF00204) | Homo sapiens (human) | DNA topoisomerase II, alpha isozyme |
| 2 | E, H, K, N (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 3 | F, J, L, P (A, B, C, D) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 4 | Chemie (ADP) | |||
| 4 | G (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | I, M, O (B, C, D) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 134 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 182642.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2186.3 | |
| All* | Total formula weight | 184828.4 |
