Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006265 | biological_process | DNA topological change |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006265 | biological_process | DNA topological change |
| C | 0003677 | molecular_function | DNA binding |
| C | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0006265 | biological_process | DNA topological change |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0006265 | biological_process | DNA topological change |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 501 |
| Chain | Residue |
| A | ASN91 |
| A | ADP502 |
| A | HOH601 |
| A | HOH633 |
| A | HOH635 |
| site_id | AC2 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE ADP A 502 |
| Chain | Residue |
| A | ILE125 |
| A | ILE141 |
| A | PHE142 |
| A | SER148 |
| A | SER149 |
| A | ASN150 |
| A | GLY161 |
| A | ARG162 |
| A | ASN163 |
| A | GLY164 |
| A | TYR165 |
| A | GLY166 |
| A | ALA167 |
| A | LYS168 |
| A | MG501 |
| A | HOH601 |
| A | HOH635 |
| B | TYR34 |
| A | ASN91 |
| A | ASN95 |
| A | ARG98 |
| A | ASN120 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 503 |
| Chain | Residue |
| A | TYR50 |
| A | LYS83 |
| A | ASN163 |
| A | TYR165 |
| A | GLY166 |
| A | LYS378 |
| A | HOH635 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 501 |
| Chain | Residue |
| B | ASN91 |
| B | ADP503 |
| B | HOH644 |
| B | HOH645 |
| B | HOH646 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 B 502 |
| Chain | Residue |
| B | GLU87 |
| B | ARG162 |
| B | ASN163 |
| B | GLY164 |
| B | TYR165 |
| B | GLY166 |
| B | LYS378 |
| B | ADP503 |
| B | HOH645 |
| site_id | AC6 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE ADP B 503 |
| Chain | Residue |
| A | TYR34 |
| B | ASN91 |
| B | ASN95 |
| B | ASN120 |
| B | ILE125 |
| B | ILE141 |
| B | PHE142 |
| B | SER148 |
| B | SER149 |
| B | ASN150 |
| B | GLY161 |
| B | ARG162 |
| B | ASN163 |
| B | GLY164 |
| B | TYR165 |
| B | GLY166 |
| B | ALA167 |
| B | LYS168 |
| B | MG501 |
| B | SO4502 |
| B | HOH603 |
| B | HOH606 |
| B | HOH612 |
| B | HOH645 |
| B | HOH646 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG C 501 |
| Chain | Residue |
| C | ASN91 |
| C | ADP502 |
| C | HOH602 |
| C | HOH607 |
| C | HOH638 |
| site_id | AC8 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE ADP C 502 |
| Chain | Residue |
| C | HOH610 |
| C | HOH638 |
| D | TYR34 |
| C | ASN91 |
| C | ASN95 |
| C | ASN120 |
| C | ILE125 |
| C | ILE141 |
| C | PHE142 |
| C | SER148 |
| C | SER149 |
| C | ASN150 |
| C | GLY161 |
| C | ARG162 |
| C | ASN163 |
| C | GLY164 |
| C | TYR165 |
| C | GLY166 |
| C | ALA167 |
| C | LYS168 |
| C | MG501 |
| C | SO4503 |
| C | HOH603 |
| C | HOH607 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 C 503 |
| Chain | Residue |
| C | GLU87 |
| C | ASN163 |
| C | TYR165 |
| C | GLY166 |
| C | LYS378 |
| C | ADP502 |
| C | HOH607 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG D 501 |
| Chain | Residue |
| D | ASN91 |
| D | ADP503 |
| D | HOH609 |
| D | HOH610 |
| D | HOH611 |
| site_id | BC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 D 502 |
| Chain | Residue |
| D | GLU87 |
| D | ARG162 |
| D | ASN163 |
| D | GLY164 |
| D | TYR165 |
| D | GLY166 |
| D | LYS378 |
| D | ADP503 |
| D | HOH611 |
| site_id | BC3 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE ADP D 503 |
| Chain | Residue |
| C | TYR34 |
| D | ASN91 |
| D | ASN95 |
| D | ASN120 |
| D | ILE125 |
| D | ILE141 |
| D | PHE142 |
| D | SER148 |
| D | SER149 |
| D | ASN150 |
| D | GLY161 |
| D | ARG162 |
| D | ASN163 |
| D | GLY164 |
| D | TYR165 |
| D | GLY166 |
| D | ALA167 |
| D | LYS168 |
| D | MG501 |
| D | SO4502 |
| D | HOH610 |
| D | HOH611 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 44 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16100112","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25202966","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16100112","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25202966","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 36 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Region: {"description":"Interaction with DNA","evidences":[{"source":"PubMed","id":"23022727","evidenceCode":"ECO:0000305"}]} |
