4R10

A conserved phosphorylation switch controls the interaction between cadherin and beta-catenin in vitro and in vivo

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Protein humpback-2	polymer	572	62334.6	1	UniProt (O44326) Pfam (PF00514) In PDB	Caenorhabditis elegans (roundworm)
2	B	Cadherin-related hmr-1	polymer	84	9479.1	1	UniProt (Q967F4) Pfam (PF22417) In PDB	Caenorhabditis elegans (roundworm)	Protein Hammerhead
3	A	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
4	A	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
5		water	water		18.0	186	Chemie (HOH)

Sequence modifications

A: 53 - 621 (UniProt: O44326)

PDB	External Database	Details
Gly 50	-	EXPRESSION TAG
Gly 51	-	EXPRESSION TAG
Ile 52	-	EXPRESSION TAG

B: 1144 - 1223 (UniProt: Q967F4)

PDB	External Database	Details
Gly 1140	-	EXPRESSION TAG
Gly 1141	-	EXPRESSION TAG
Ile 1142	-	EXPRESSION TAG
Gln 1143	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	71813.6
Non-Polymers*	Number of molecules	2
	Total formula weight	158.1
All*	Total formula weight	71971.8

*Water molecules are not included.