4QYI

1.95 Angstrom resolution crystal structure of a hypoxanthine-guanine phosphoribosyltransferase (hpt-2) from Bacillus anthracis str. 'Ames Ancestor' with HEPES molecule in the active site

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Hypoxanthine phosphoribosyltransferase	polymer	186	21127.2	1	UniProt (Q81KC7) Pfam (PF00156) UniProt (by SIFTS) (A0A6L8PVA4) In PDB	Bacillus anthracis (anthrax anthrax bacterium)
2	B, C, D, E	Hypoxanthine phosphoribosyltransferase	polymer	186	21203.3	4	UniProt (Q81KC7) Pfam (PF00156) UniProt (by SIFTS) (A0A6L8PVA4) In PDB	Bacillus anthracis (anthrax anthrax bacterium)
3	A, B, C, D, E	MAGNESIUM ION	non-polymer		24.3	9	Chemie (MG)
4	A, B, C, D, E	PHOSPHATE ION	non-polymer		95.0	8	Chemie (PO4)
5	B, C, E	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID	non-polymer		238.3	3	Chemie (EPE)
6	E	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
7		water	water		18.0	370	Chemie (HOH)

Sequence modifications

A: 1 - 183 (UniProt: Q81KC7)

PDB	External Database	Details
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

B, C, D, E: 1 - 183 (UniProt: Q81KC7)

PDB	External Database	Details
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	105940.6
Non-Polymers*	Number of molecules	21
	Total formula weight	1785.5
All*	Total formula weight	107726.1

*Water molecules are not included.