4QXF
crystal structure of human LGR4 and Rspo1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Leucine-rich repeat-containing G-protein coupled receptor 4, Variable lymphocyte receptor B | polymer | 301 | 33151.8 | 2 | UniProt (Q9BXB1) UniProt (Q4G1L2) Pfam (PF01462) Pfam (PF13855) Pfam (PF11921) | Homo sapiens (human Inshore hagfish) | G-protein coupled receptor 48 |
| 2 | C, D (E, C) | R-spondin-1 | polymer | 102 | 11185.0 | 2 | UniProt (Q2MKA7) Pfam (PF15913) | Homo sapiens (human) | Roof plate-specific spondin-1, hRspo1 |
| 3 | E, F, G, H (A, B, E, C) | water | water | 18.0 | 263 | Chemie (HOH) |
Sequence modifications
A, B: 27 - 252 (UniProt: Q9BXB1)
A, B: 253 - 325 (UniProt: Q4G1L2)
| PDB | External Database | Details |
|---|---|---|
| Met 25 | - | expression tag |
| Asp 26 | - | expression tag |
| Gly 75 | Asp 75 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 88673.6 | |
| All* | Total formula weight | 88673.6 |
