4QT2
Crystal Structure of the FK506-Binding Domain of Plasmodium Falciparum FKBP35 in complex with Rapamycin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | FK506-binding protein (FKBP)-type peptidyl-propyl isomerase | polymer | 131 | 14828.7 | 1 | UniProt (Q8I4V8) Pfam (PF00254) | Plasmodium falciparum 3D7 | |
| 2 | B (A) | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 3 | C (A) | RAPAMYCIN IMMUNOSUPPRESSANT DRUG | non-polymer | 914.2 | 1 | Chemie (RAP) | |||
| 4 | D (A) | water | water | 18.0 | 99 | Chemie (HOH) |
Sequence modifications
A: 7 - 127 (UniProt: Q8I4V8)
| PDB | External Database | Details |
|---|---|---|
| Leu 128 | - | expression tag |
| Glu 129 | - | expression tag |
| Thr 130 | - | expression tag |
| Ser 131 | - | expression tag |
| His 132 | - | expression tag |
| His 133 | - | expression tag |
| His 134 | - | expression tag |
| His 135 | - | expression tag |
| His 136 | - | expression tag |
| His 137 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14828.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 983.3 | |
| All* | Total formula weight | 15812.0 |
