4QRH
Molecular mechanism and evolution of guanylate kinase regulation by (p)ppGpp
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Guanylate kinase | polymer | 210 | 24345.7 | 4 | UniProt (W6E076) Pfam (PF00625) UniProt (by SIFTS) (A0A0J9X1Z9) | Staphylococcus aureus USA300-ISMMS1 | GMP kinase |
| 2 | E, K (A, C) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | F, I, M (B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 4 | G, J, N (B, C, D) | POTASSIUM ION | non-polymer | 39.1 | 3 | Chemie (K) | |||
| 5 | H, L, R (B, C, D) | guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate) | non-polymer | 683.1 | 3 | Chemie (0O2) | |||
| 6 | O, P, Q (D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 7 | S, T, U, V (A, B, C, D) | water | water | 18.0 | 629 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 207 (UniProt: W6E076)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 97382.7 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2618.0 | |
| All* | Total formula weight | 100000.7 |
