4QQN
Protein arginine methyltransferase 3 in complex with compound MTV044246
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | PRMT3 protein | polymer | 340 | 38281.9 | 1 | UniProt (Q8WUV3) Pfam (PF06325) Pfam (PF22528) UniProt (by SIFTS) (O60678) In PDB | Homo sapiens (human) | |
2 | A | 1-{2-[1-(aminomethyl)cyclohexyl]ethyl}-3-isoquinolin-6-ylurea | non-polymer | 326.4 | 1 | Chemie (3BQ) | |||
3 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
4 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
5 | A | UNKNOWN ATOM OR ION | non-polymer | 12 | Chemie (UNX) | ||||
6 | water | water | 18.0 | 156 | Chemie (HOH) |
Sequence modifications
A: 228 - 548 (UniProt: Q8WUV3)
PDB | External Database | Details |
---|---|---|
Met 209 | - | expression tag |
Gly 210 | - | expression tag |
Ser 211 | - | expression tag |
Ser 212 | - | expression tag |
His 213 | - | expression tag |
His 214 | - | expression tag |
His 215 | - | expression tag |
His 216 | - | expression tag |
His 217 | - | expression tag |
His 218 | - | expression tag |
Ser 219 | - | expression tag |
Ser 220 | - | expression tag |
Gly 221 | - | expression tag |
Leu 222 | - | expression tag |
Val 223 | - | expression tag |
Pro 224 | - | expression tag |
Arg 225 | - | expression tag |
Gly 226 | - | expression tag |
Ser 227 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 38281.9 | |
Non-Polymers* | Number of molecules | 15 |
Total formula weight | 454.0 | |
All* | Total formula weight | 38735.9 |