4QOK
Structural basis for ineffective T-cell responses to MHC anchor residue improved heteroclitic peptides
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA class I histocompatibility antigen, A-2 alpha chain | polymer | 276 | 31951.3 | 1 | UniProt (P01892) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P04439) | Homo sapiens (human) | MHC class I antigen A*2 |
| 2 | B (B) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | Beta-2-microglobulin form pI 5.3 |
| 3 | C (C) | Melanoma antigen recognized by T-cells 1 marker peptide | polymer | 10 | 943.1 | 1 | UniProt (Q16655) | Homo sapiens | MART-1, Antigen LB39-AA, Antigen SK29-AA, Protein Melan-A |
| 4 | D (D) | Mel5 TCR chain alpha | polymer | 194 | 21371.4 | 1 | Homo sapiens | ||
| 5 | E (E) | Mel5 TCR chain beta | polymer | 244 | 27264.4 | 1 | Homo sapiens | ||
| 6 | F, G, H, I (A, D, E) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 7 | J, K, L (A, D, E) | water | water | 18.0 | 21 | Chemie (HOH) |
Sequence modifications
B: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 93409.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 248.3 | |
| All* | Total formula weight | 93657.8 |
