4QMX
MST3 in complex with SARACATINIB
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SERINE/THREONINE-PROTEIN KINASE 24 | polymer | 310 | 35023.9 | 1 | UniProt (Q9Y6E0) Pfam (PF00069) | Homo sapiens (human) | STE20-LIKE KINASE MST3, MST-3, MAMMALIAN STE20-LIKE PROTEIN KINASE 3 |
| 2 | B (A) | N-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-7-[2-(4-METHYLPIPERAZIN-1-YL)ETHOXY]-5-(TETRAHYDRO-2H-PYRAN-4-YLOXY)QUINAZOLIN-4-AMINE | non-polymer | 542.0 | 1 | Chemie (H8H) | |||
| 3 | C (A) | water | water | 18.0 | 163 | Chemie (HOH) |
Sequence modifications
A: 1 - 303 (UniProt: Q9Y6E0)
| PDB | External Database | Details |
|---|---|---|
| Gly -6 | - | expression tag |
| Pro -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Phe 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35023.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 542.0 | |
| All* | Total formula weight | 35566.0 |
