4QMW
MST3 IN COMPLEX WITH PP-121, 1-CYCLOPENTYL-3-(1H-PYRROLO[2,3-B]PYRIDIN-5-YL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | SERINE/THREONINE-PROTEIN KINASE 24 | polymer | 310 | 35023.9 | 1 | UniProt (Q9Y6E0) Pfam (PF00069) In PDB | Homo sapiens (human) | STE20-LIKE KINASE MST3, MST-3, MAMMALIAN STE20-LIKE PROTEIN KINASE 3 |
2 | A | 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | non-polymer | 319.4 | 1 | Chemie (KS1) | |||
3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
4 | A | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
5 | water | water | 18.0 | 177 | Chemie (HOH) |
Sequence modifications
A: 1 - 303 (UniProt: Q9Y6E0)
PDB | External Database | Details |
---|---|---|
Gly -6 | - | expression tag |
Pro -5 | - | expression tag |
Leu -4 | - | expression tag |
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
Glu -1 | - | expression tag |
Phe 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 35023.9 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 440.5 | |
All* | Total formula weight | 35464.4 |