4QJI

Crystal Structure of the C-terminal CTP-binding domain of a Phosphopantothenoylcysteine decarboxylase/phosphopantothenate-cysteine ligase with bound CTP from Mycobacterium smegmatis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Phosphopantothenate--cysteine ligase	polymer	237	24774.0	2	UniProt (A0QWT2) Pfam (PF04127)	Mycobacterium smegmatis	Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase,Probable coenzyme A biosynthesis bifunctional protein CoaBC
2	C, E (A, B)	CYTIDINE-5'-TRIPHOSPHATE	non-polymer		483.2	2	Chemie (CTP)
3	D, F (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	G, H (A, B)	water	water		18.0	23	Chemie (HOH)

Sequence modifications

A, B: 186 - 414 (UniProt: A0QWT2)

PDB	External Database	Details
Met 178	-	initiating methionine
Ala 179	-	expression tag
His 180	-	expression tag
His 181	-	expression tag
His 182	-	expression tag
His 183	-	expression tag
His 184	-	expression tag
His 185	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	49548.0
Non-Polymers*	Number of molecules	4
	Total formula weight	1014.9
All*	Total formula weight	50562.9

*Water molecules are not included.