4QJI
Crystal Structure of the C-terminal CTP-binding domain of a Phosphopantothenoylcysteine decarboxylase/phosphopantothenate-cysteine ligase with bound CTP from Mycobacterium smegmatis
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE CTP A 500 |
| Chain | Residue |
| A | MET275 |
| A | LYS350 |
| A | ARG353 |
| A | LYS354 |
| A | MG501 |
| B | LYS291 |
| B | LYS294 |
| A | ALA277 |
| A | VAL279 |
| A | ASP281 |
| A | ASP308 |
| A | ASP309 |
| A | VAL310 |
| A | LEU311 |
| A | PHE332 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG A 501 |
| Chain | Residue |
| A | ASP281 |
| A | CTP500 |
| A | HOH602 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE CTP B 500 |
| Chain | Residue |
| B | MET275 |
| B | ALA277 |
| B | VAL279 |
| B | ASP281 |
| B | ASP308 |
| B | ASP309 |
| B | VAL310 |
| B | LEU311 |
| B | PHE332 |
| B | LYS350 |
| B | LYS354 |
| B | MG501 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG B 501 |
| Chain | Residue |
| B | ASP281 |
| B | CTP500 |
| B | HOH602 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"33420031","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUN-2014","submissionDatabase":"PDB data bank","title":"Crystal structure of the C-terminal CTP-binding domain of a phosphopantothenoylcysteine decarboxylase/phosphopantothenate-cysteine ligase with bound CTP from Mycobacterium smegmatis.","authors":["Dranow D.M.","Abendroth J.","Wernimont A.K.","Edwards T.E.","Lorimer D."]}},{"source":"PDB","id":"4QJI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6TH2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6THC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_02225","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"33420031","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUN-2014","submissionDatabase":"PDB data bank","title":"Crystal structure of the C-terminal CTP-binding domain of a phosphopantothenoylcysteine decarboxylase/phosphopantothenate-cysteine ligase with bound CTP from Mycobacterium smegmatis.","authors":["Dranow D.M.","Abendroth J.","Wernimont A.K.","Edwards T.E.","Lorimer D."]}},{"source":"PDB","id":"4QJI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6TH2","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_02225","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"33420031","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUN-2014","submissionDatabase":"PDB data bank","title":"Crystal structure of the C-terminal CTP-binding domain of a phosphopantothenoylcysteine decarboxylase/phosphopantothenate-cysteine ligase with bound CTP from Mycobacterium smegmatis.","authors":["Dranow D.M.","Abendroth J.","Wernimont A.K.","Edwards T.E.","Lorimer D."]}},{"source":"PDB","id":"4QJI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6THC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_02225","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"33420031","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUN-2014","submissionDatabase":"PDB data bank","title":"Crystal structure of the C-terminal CTP-binding domain of a phosphopantothenoylcysteine decarboxylase/phosphopantothenate-cysteine ligase with bound CTP from Mycobacterium smegmatis.","authors":["Dranow D.M.","Abendroth J.","Wernimont A.K.","Edwards T.E.","Lorimer D."]}},{"source":"PDB","id":"4QJI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6TH2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6THC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"33420031","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6TH2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6THC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
