4QJ4
Structure of a fragment of human phospholipase C-beta3 delta472-569, bound to IP3 and in complex with Galphaq
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Guanine nucleotide-binding protein G(q) subunit alpha | polymer | 379 | 44711.6 | 1 | UniProt (P21279) Pfam (PF00503) In PDB | Mus musculus (mouse) | Guanine nucleotide-binding protein alpha-q |
2 | B | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 | polymer | 793 | 90294.2 | 1 | UniProt (Q01970) Pfam (PF17787) Pfam (PF22631) Pfam (PF00388) Pfam (PF00387) Pfam (PF00168) In PDB | Homo sapiens (human) | Phosphoinositide phospholipase C-beta-3, Phospholipase C-beta-3, PLC-beta-3 |
3 | A | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
4 | A | TETRAFLUOROALUMINATE ION | non-polymer | 103.0 | 1 | Chemie (ALF) | |||
5 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
6 | B | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
7 | B | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE | non-polymer | 420.1 | 1 | Chemie (I3P) | |||
8 | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence modifications
A: 7 - 359 (UniProt: P21279)
B: 10 - 470 (UniProt: Q01970)
B: 570 - 891 (UniProt: Q01970)
PDB | External Database | Details |
---|---|---|
Met -19 | - | expression tag |
Ser -18 | - | expression tag |
Tyr -17 | - | expression tag |
Tyr -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
Asp -9 | - | expression tag |
Tyr -8 | - | expression tag |
Asp -7 | - | expression tag |
Ile -6 | - | expression tag |
Pro -5 | - | expression tag |
Thr -4 | - | expression tag |
Thr -3 | - | expression tag |
Glu -2 | - | expression tag |
Asn -1 | - | expression tag |
Leu 0 | - | expression tag |
Tyr 1 | - | expression tag |
Phe 2 | - | expression tag |
Gln 3 | - | expression tag |
Gly 4 | - | expression tag |
Ala 5 | - | expression tag |
Ala 6 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met 0 | - | expression tag |
Ala 1 | - | expression tag |
His 2 | - | expression tag |
His 3 | - | expression tag |
His 4 | - | expression tag |
His 5 | - | expression tag |
His 6 | - | expression tag |
His 7 | - | expression tag |
Gly 8 | - | expression tag |
Thr 9 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 135005.7 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 1030.7 | |
All* | Total formula weight | 136036.4 |