4QJ3
Structure of a fragment of human phospholipase C-beta3 delta472-559, in complex with Galphaq
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein G(q) subunit alpha | polymer | 379 | 44711.6 | 1 | UniProt (P21279) Pfam (PF00503) | Mus musculus (mouse) | Guanine nucleotide-binding protein alpha-q |
| 2 | B (B) | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 | polymer | 793 | 90294.2 | 1 | UniProt (Q01970) Pfam (PF17787) Pfam (PF22631) Pfam (PF00388) Pfam (PF00387) Pfam (PF00168) | Homo sapiens (human) | Phosphoinositide phospholipase C-beta-3, Phospholipase C-beta-3, PLC-beta-3 |
| 3 | C (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 4 | D (A) | TETRAFLUOROALUMINATE ION | non-polymer | 103.0 | 1 | Chemie (ALF) | |||
| 5 | E (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | F (B) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 7 | G, H (A, B) | water | water | 18.0 | 28 | Chemie (HOH) |
Sequence modifications
A: 7 - 359 (UniProt: P21279)
B: 10 - 470 (UniProt: Q01970)
B: 570 - 891 (UniProt: Q01970)
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | expression tag |
| Ser -18 | - | expression tag |
| Tyr -17 | - | expression tag |
| Tyr -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Asp -9 | - | expression tag |
| Tyr -8 | - | expression tag |
| Asp -7 | - | expression tag |
| Ile -6 | - | expression tag |
| Pro -5 | - | expression tag |
| Thr -4 | - | expression tag |
| Thr -3 | - | expression tag |
| Glu -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Leu 0 | - | expression tag |
| Tyr 1 | - | expression tag |
| Phe 2 | - | expression tag |
| Gln 3 | - | expression tag |
| Gly 4 | - | expression tag |
| Ala 5 | - | expression tag |
| Ala 6 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | expression tag |
| Ala 1 | - | expression tag |
| His 2 | - | expression tag |
| His 3 | - | expression tag |
| His 4 | - | expression tag |
| His 5 | - | expression tag |
| His 6 | - | expression tag |
| His 7 | - | expression tag |
| Gly 8 | - | expression tag |
| Thr 9 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 135005.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 610.6 | |
| All* | Total formula weight | 135616.3 |
