4QGE
phosphodiesterase-9A in complex with inhibitor WYQ-C36D
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Phosphodiesterase 9A | polymer | 533 | 61789.1 | 2 | UniProt (K7AGW3) Pfam (PF00233) UniProt (by SIFTS) (H2QL32) | Pan troglodytes (Chimpanzee) | |
| 2 | C, F (A, B) | N~2~-(1-cyclopentyl-4-oxo-4,7-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl)-N-(4-methoxyphenyl)-D-alaninamide | non-polymer | 396.4 | 2 | Chemie (35O) | |||
| 3 | D, G (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 299 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 533 (UniProt: K7AGW3)
| PDB | External Database | Details |
|---|---|---|
| Lys 276 | Asn 276 | conflict |
| Thr 280 | Met 280 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 123578.2 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 972.3 | |
| All* | Total formula weight | 124550.5 |
